DL-Carnitine → Cyclohexyl acetyl carnitine chloride

HRID 35373

반응식

HRID 35373 반응식
[CH3:1][N+:2]([CH2:5][CH:6]([OH:11])[CH2:7][C:8]([O-:10])=[O:9])([CH3:4])[CH3:3].[CH:12]1(CC([Cl:21])=O)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.[CH2:22]([O:24]CC)[CH3:23]>FC(F)(F)C(O)=O>[CH:12]1([CH:5]([N+:2]([CH3:3])([CH3:4])[CH3:1])[C:6]([C:22](=[O:24])[CH3:23])([CH2:7][C:8](=[O:10])[O-:9])[OH:11])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.[Cl-:21]

참가 물질

5

반응물 3

HCID 288DL-CarnitineHCID 3283Diethyl EtherHCID 2757989Cyclohexylacetyl chloride

생성물 1

HCID 131715698Cyclohexyl acetyl carnitine chloride

시약·촉매·용매 1

HCID 6422Trifluoroacetic acid용매

실험 절차

Carnitine chloride (2.97 g; 0.01 moles) was dissolved in trifluoro acetic acid (10 cc). To this solution was added cyclohexyl acetyl chloride (0.01 moles) prepared as previously disclosed and the resulting mixture was kept under stirring for 48 hours. Ethyl ether was then added and the resulting mixture was kept under stirring for 0.5 hours at 0° C. A precipitate was obtained, which was filtered off and dried under vacuum.

후처리

  1. customprepared
  2. stirringunder stirring for 0.5 hours at 0° C
  3. customA precipitate was obtained
  4. filtrationwhich was filtered off
  5. customdried under vacuum

출처 및 근거

ORD 기록
ord-ccb56ca24b4b4916a6432cb595293d2a
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04766222

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