Sodium Hydroxide → 8-[2-Oxo-3-(3-trifluoromethylbenzyl)-benzimidazolin-1-yl]-caprylic acid

HRID 355068노트

반응식

HRID 355068 반응식
C[O:2][C:3](=[O:32])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[N:13]([CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([C:27]([F:30])([F:29])[F:28])[CH:22]=2)[C:12]1=[O:31].[OH-].[Na+]>>[O:31]=[C:12]1[N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:32])=[O:2])[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[N:13]1[CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([C:27]([F:30])([F:28])[F:29])[CH:22]=1

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 542601018-[2-Oxo-3-(3-trifluoromethylbenzyl)-benzimidazolin-1-yl]-caprylic acid methyl ester

생성물 1

HCID 205069418-[2-Oxo-3-(3-trifluoromethylbenzyl)-benzimidazolin-1-yl]-caprylic acid

실험 절차

The product is produced as described in example 22 from 5.7 g. of 8-[2-oxo-3-(3-trifluoromethylbenzyl)-benzimidazolin-1-yl]-caprylic acid methyl ester and 1.5 g. of NaOH.

후처리

  1. customThe product is produced

출처 및 근거

ORD 기록
ord-a81e9369162b484998ec060cdf3891f7
출처 데이터셋
uspto-grants-1983_03
특허 번호
US04377695

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