2,3-Dimethylbenzoyl chloride → HCID 67623756, 화합물

HRID 355886

반응식

HRID 355886 반응식
[NH2:1][C:2]1[CH:24]=[CH:23][C:5]([C:6]([N:8]2[CH2:14][C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[CH2:11][C:10]3[CH:19]=[CH:20][CH:21]=[CH:22][C:9]2=3)=[O:7])=[CH:4][CH:3]=1.[CH3:25][C:26]1[C:34]([CH3:35])=[CH:33][CH:32]=[CH:31][C:27]=1[C:28](Cl)=[O:29]>ClCCl>[CH:19]1[C:10]2[CH2:11][C:12]3[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=3[CH2:14][N:8]([C:6]([C:5]3[CH:4]=[CH:3][C:2]([NH:1][C:28](=[O:29])[C:27]4[CH:31]=[CH:32][CH:33]=[C:34]([CH3:35])[C:26]=4[CH3:25])=[CH:24][CH:23]=3)=[O:7])[C:9]=2[CH:22]=[CH:21][CH:20]=1

참가 물질

4

반응물 2

HCID 28008992,3-Dimethylbenzoyl chlorideHCID 154104675-(4-Aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine

생성물 1

HCID 67623756HCID 67623756, 화합물수율 13.4%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

As described for Example 9, 0.628 g (2 mmol) of 5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine is reacted with 0.506 g (3.0 mmol) of 2,3-dimethylbenzoyl chloride in dichloromethane. The product is recrystallized from hexane-dichloromethane to give 0.12 g of crystals, m.p. 138°-142° C.

후처리

  1. customThe product is recrystallized from hexane-dichloromethane

출처 및 근거

ORD 기록
ord-20d1bc6099d94f4b9ad4fa8e77c80f59
출처 데이터셋
uspto-grants-1998_11
특허 번호
US05834461

연결된 노트

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