1-Acetylamino-6,7,8,9-tetrahydro-5H-benzocycloheptene-9-one → 1,8-Diacetylamino-6,7,8,9-tetrahydro-5H-benzocycloheptene-9-one

HRID 355964

반응식

HRID 355964 반응식
[C:1]([NH:4][C:5]1[C:10]2[C:11](=[O:16])[CH2:12][CH2:13][CH2:14][CH2:15][C:9]=2[CH:8]=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[C:17]([NH:20]C1C=CC=C2C=1C(=O)CCC2)(=[O:19])[CH3:18]>>[C:1]([NH:4][C:5]1[C:10]2[C:11](=[O:16])[CH:12]([NH:20][C:17](=[O:19])[CH3:18])[CH2:13][CH2:14][CH2:15][C:9]=2[CH:8]=[CH:7][CH:6]=1)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 103532981-Acetylamino-6,7,8,9-tetrahydro-5H-benzocycloheptene-9-oneHCID 12119265N-(8-Oxo-5,6,7,8-tetrahydronaphthalen-1-YL)acetamide

생성물 1

HCID 224494531,8-Diacetylamino-6,7,8,9-tetrahydro-5H-benzocycloheptene-9-one

실험 절차

The reaction was carried out in the same manner as in Example 1-(2), except that 270 mg of the compound prepared in (2) above was used instead of 8-acetylamino-1-tetralone of Example 1-(2). The reaction mixture obtained by the post-treatment was further reacted in the same manner as in Example 1-(3) and post-treated to produce 126 mg of the title compound.

후처리

  1. customThe reaction mixture obtained by the post-treatment
  2. additionpost-treated

출처 및 근거

ORD 기록
ord-a6c9eea160d542618b7334d21eca165d
출처 데이터셋
uspto-grants-1998_11
특허 번호
US05834476

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