Dimethylformamide → 4-(3-Dimethylaminophenoxy)butyronitrile
반응식
[CH3:1][N:2]([CH3:10])[C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1.C(=O)([O-])[O-].[K+].[K+].CN(C)C=O.Br[CH2:23][CH2:24][CH2:25][C:26]#[N:27]>O>[CH3:1][N:2]([CH3:10])[C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][CH:8]=1)[O:9][CH2:23][CH2:24][CH2:25][C:26]#[N:27]참가 물질
6
실험 절차
A suspension of 3-dimethylaminophenol (5 g), potassium carbonate (10.05 g) and dimethylformamide (85 ml) was stirred at room temperature for 5 hours. 4-Bromobutyronitrile (7.3 ml) was added and the suspension stirred for 17 hours. The reaction mixture was poured into water and extracted with ethyl acetate. The extracts were washed with water, dried and the solvent removed to yield 4-(3-dimethylaminophenoxy)butyronitrile.
후처리
- stirringthe suspension stirred for 17 hours
- extractionextracted with ethyl acetate
- washThe extracts were washed with water
- customdried
- customthe solvent removed
출처 및 근거
- ORD 기록
- ord-7c7eb924af47428b8286be45c1256f2f
- 출처 데이터셋
- uspto-grants-1988_08
- 특허 번호
- US04767769
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