Sodium cyanoborohydride → 5-(3-Thienyl)indoline

HRID 356028노트

반응식

HRID 356028 반응식
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:7]=[C:8]3[C:12](=[CH:13][CH:14]=2)[NH:11][CH:10]=[CH:9]3)=[CH:2]1.C([BH3-])#N.[Na+]>C(O)(=O)C>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:7]=[C:8]3[C:12](=[CH:13][CH:14]=2)[NH:11][CH2:10][CH2:9]3)=[CH:2]1

참가 물질

4

반응물 2

HCID 5003444Sodium cyanoborohydrideHCID 149732275-(Thiophen-3-yl)-1H-indole

생성물 1

HCID 200999545-(3-Thienyl)indoline수율 100%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

5-(3-Thienyl)indole D40 was reduced in the usual way with sodium cyano borohydride in glacial acetic acid to give the title compound (D41) (1.0 g, 100%).

출처 및 근거

ORD 기록
ord-897ff97657e549949f21d17da38e6886
출처 데이터셋
uspto-grants-1998_11
특허 번호
US05834494

반응 노트

불러오는 중…