Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol hydrochloride → (3aR*,10aS*)-9-Benzyl-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol hydrochloride | HCID 21887872 | — |
| 반응물 | (3aR*,10aS*)-9-benzyl-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta [e][1,4]diazepin-10(1H)-one | HCID 70109795 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (3aR*,10aS*)-9-Benzyl-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one hydrochloride | HCID 70111935 | — |
반응 단계
In ethanol was dissolved (3aR*,10aS*)-9-benzyl-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one. To the solution was added dropwise a 2.5N HCl-ethanol solution, and the mixture was concentrated under reduced pressure. The concentrate was recrystallized from ethanol-ether to give the titled compound. m.p. 145°-148° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05834463 |
| 출처 데이터셋 | uspto-grants-1998_11 |
| ORD ID | ord-73df44f84f6d41899bb8ef19f4c809a0 |
| 출처 메모 | uspto-grants-1998_11 |