Hydrochloric Acid → 5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-8-yloxy)butyl]thiazolidine-2,4-dione hydrochloride
반응식
[CH:1](=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][CH2:13][CH2:14][O:15][C:16]2[C:17]3[N:18]([CH:22]=[CH:23][N:24]=3)[CH:19]=[CH:20][CH:21]=2)[C:6]1=[O:25])[CH2:2][CH2:3][CH3:4].[ClH:26]>CO>[ClH:26].[CH:1](=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][CH2:13][CH2:14][O:15][C:16]2[C:17]3[N:18]([CH:22]=[CH:23][N:24]=3)[CH:19]=[CH:20][CH:21]=2)[C:6]1=[O:25])[CH2:2][CH2:3][CH3:4]참가 물질
4
실험 절차
To a solution of 1.44 g (4.0 mmol) of 5-butylidene-3-[4-(imidazo[1,2-a]pyridin-8-yloxy)butyl]thiazolidine-2,4-dione in 20 ml of methanol, 0.4 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.58 g (quant, yellow oily substance) of the desired product.