Hydrochloric Acid → 5-Nonylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

HRID 357175노트

반응식

HRID 357175 반응식
[CH:1](=[C:10]1[S:14][C:13](=[O:15])[N:12]([CH2:16][CH2:17][CH2:18][CH2:19][S:20][C:21]2[N:26]3[CH:27]=[CH:28][N:29]=[C:25]3[CH:24]=[CH:23][CH:22]=2)[C:11]1=[O:30])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[ClH:31]>CO>[ClH:31].[CH:1](=[C:10]1[S:14][C:13](=[O:15])[N:12]([CH2:16][CH2:17][CH2:18][CH2:19][S:20][C:21]2[N:26]3[CH:27]=[CH:28][N:29]=[C:25]3[CH:24]=[CH:23][CH:22]=2)[C:11]1=[O:30])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 571716265-Nonylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione

생성물 1

HCID 734729195-Nonylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a solution of 1.96 g (4.40 mmol) of 5-nonylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 30 ml of methanol, 0.42 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 2.01 g (94.8%, yellow-orange oily substance) of the desired product.

후처리

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

출처 및 근거

ORD 기록
ord-b2496a958ab249b8918063693c3f13e5
출처 데이터셋
uspto-grants-1998_11
특허 번호
US05840732

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