5-(4-Chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione → 5-(4-Chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione hydrochloride

HRID 357177

반응식

HRID 357177 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[C:9]2[O:13][C:12](=[O:14])[N:11]([CH2:15][CH2:16][CH2:17][CH2:18][S:19][C:20]3[N:25]4[CH:26]=[CH:27][N:28]=[C:24]4[CH:23]=[CH:22][CH:21]=3)[C:10]2=[O:29])=[CH:4][CH:3]=1>CO.Cl>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]=[C:9]2[O:13][C:12](=[O:14])[N:11]([CH2:15][CH2:16][CH2:17][CH2:18][S:19][C:20]3[N:25]4[CH:26]=[CH:27][N:28]=[C:24]4[CH:23]=[CH:22][CH:21]=3)[C:10]2=[O:29])=[CH:6][CH:7]=1

참가 물질

4

반응물 1

HCID 543485705-(4-Chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione

생성물 1

HCID 702053545-(4-Chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione hydrochloride

시약·촉매·용매 2

HCID 313Hydrochloric Acid용매HCID 887Methanol용매

실험 절차

To a solution of 0.301 g (0.70 mmol) of 5-(4-chlorophenyl)methylene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione in 10 ml of methanol, 0.10 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was crystallized by the addition of diethyl ether to yield 0.223 g (68.6%, light pink crystal) of the desired product.

후처리

  1. distillationAfter the solvent was distilled off
  2. customthe residue was crystallized by the addition of diethyl ether

출처 및 근거

ORD 기록
ord-ddfa37448dd64177b4b7a815fc9c0367
출처 데이터셋
uspto-grants-1998_11
특허 번호
US05840732

연결된 노트

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