Butyl isocyanate → 1-Phenyl-3-n-butyl hydantoin

반응식

[C:1]1([NH:7][CH2:8][C:9]([OH:11])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:12]([N:16]=[C:17]=[O:18])[CH2:13][CH2:14][CH3:15]>>[C:1]1([N:7]2[CH2:8][C:9](=[O:11])[N:16]([CH2:12][CH2:13][CH2:14][CH3:15])[C:17]2=[O:18])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

반응물 2

HCID 8110Butyl isocyanate

HCID 66025N-Phenylglycine

생성물 1

HCID 124593331-Phenyl-3-n-butyl hydantoin수율 43.3%

실험 절차

N-phenyl glycine (0.15 mole) was added with stirring over a 15 minute period to n-butyl isocyanate (0.15 mole). After the addition was complete the reaction mixture was refluxed for about 6 hours and then allowed to stand at room temperature until it solidified. The solidified mass was crystallized from ethanol and produced 0.065 moles of the above-described product having a melting point of 74° l C.

후처리

additionAfter the addition
temperaturewas refluxed for about 6 hours
customto stand at room temperature until it
customThe solidified mass was crystallized from ethanol

출처 및 근거

ORD 기록: ord-8b448feab8ad457aab5c39656a815484
출처 데이터셋: uspto-grants-1984_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04464387

반응 노트

불러오는 중…