Diazomethane → 3-Hexynoic acid methyl ester
반응식
[C:1]([OH:8])(=[O:7])[CH2:2][C:3]#[C:4][CH2:5][CH3:6].[N+](=[CH2:11])=[N-]>CCOCC.C(O)(=O)C>[CH3:11][O:7][C:1](=[O:8])[CH2:2][C:3]#[C:4][CH2:5][CH3:6]참가 물질
5
실험 절차
A solution of 5.9 g of 3-hexynoic acid in 50 ml of ether is treated with a slight excess of ethereal diazomethane solution. A few drops of glacial acetic acid are added to the mixture, the mixture is concentrated in vacuo and then distilled. 5.65 g of the title compound are obtained: b.p. 62° C. (5 mm).
후처리
- concentrationthe mixture is concentrated in vacuo
- distillationdistilled
출처 및 근거
- ORD 기록
- ord-f9726011908648edaaa2665197868482
- 출처 데이터셋
- uspto-grants-1984_08
- 특허 번호
- US04466969
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