Methyl (Z)-7-phthalimidohept-5-enoate → (Z)-7-Phthalimidohept-5-enoic Acid
반응식
[C:1]1(=[O:21])[N:5]([CH2:6]/[CH:7]=[CH:8]\[CH2:9][CH2:10][CH2:11][C:12]([O:14]C)=[O:13])[C:4](=[O:16])[C:3]2=[CH:17][CH:18]=[CH:19][CH:20]=[C:2]12>CC(C)=O.Cl.O>[C:4]1(=[O:16])[N:5]([CH2:6]/[CH:7]=[CH:8]\[CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])[C:1](=[O:21])[C:2]2=[CH:20][CH:19]=[CH:18][CH:17]=[C:3]12참가 물질
5
실험 절차
A solution of methyl (Z)-7-phthalimidohept-5-enoate (1.56 g) in acetone (30 ml), concentrated hydrochloric acid (15 ml) and water (15 ml) was refluxed for 2.5 hours. Water (180 ml) was added and the solution was cooled. The precipitate was collected by filtration to give the title compound (1.2 g). m.p. 86°-88° C.
후처리
- temperaturethe solution was cooled
- filtrationThe precipitate was collected by filtration
출처 및 근거
- ORD 기록
- ord-2b262f54b69b4c24a4ef5f86f10f6fce
- 출처 데이터셋
- uspto-grants-1991_03
- 특허 번호
- US04997847
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