4-Methoxybenzenesulfonyl chloride → 8-(4-Methoxybenzenesulphonamido)octanoic Acid

HRID 358634노트

반응식

HRID 358634 반응식
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10].[CH3:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>[OH-].[Na+]>[CH3:12][O:13][C:14]1[CH:15]=[CH:16][C:17]([S:20]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10])(=[O:22])=[O:21])=[CH:18][CH:19]=1

참가 물질

4

반응물 2

HCID 74014-Methoxybenzenesulfonyl chlorideHCID 660858-Aminooctanoic acid

생성물 1

HCID 200669688-(4-Methoxybenzenesulphonamido)octanoic Acid

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

실험 절차

A solution of 8-aminooctanoic acid in 10% sodium hydroxide solution was treated with 4-methoxybenzenesulphonylchloride in the manner of Example 2 to give the title compound which, on recrystallisation from aqueous 2-propanol, had a melting point of 102°-103° C.

출처 및 근거

ORD 기록
ord-f5f8b95cdb084ebe9d17e567654ad659
출처 데이터셋
uspto-grants-1991_03
특허 번호
US04997847

반응 노트

불러오는 중…