Acetic Anhydride → HCID 178471962, 화합물

반응식

[CH3:1][C:2]1[C:15]([F:16])=[C:14]([F:17])[CH:13]=[C:12]([F:18])[C:3]=1[C:4]([CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])=[O:5].[CH:19]([O-])([O-])OCC.C(OC(=O)C)(=O)C.Cl.[NH2:33][C:34]1[CH:38]=[N:37][S:36][N:35]=1>>[S:36]1[N:37]=[CH:38][C:34]([NH:33][CH:19]=[C:6]([C:4](=[O:5])[C:3]2[C:12]([F:18])=[CH:13][C:14]([F:17])=[C:15]([F:16])[C:2]=2[CH3:1])[C:7]([O:9][CH2:10][CH3:11])=[O:8])=[N:35]1

참가 물질

반응물 4

HCID 7918Acetic Anhydride

HCID 14517129Ethyl (3,4,6-Trifluoro-2-methylbenzoyl)acetate

HCID 199398011,2,5-Thiadiazol-3-amine hydrochloride

HCID 53630039Ethylorthoformate

생성물 1

HCID 178471962HCID 178471962, 화합물

실험 절차

Compound No. 157 (colorless needles) was prepared in a similar manner to Example 17, proceeding from the corresponding compounds ethyl 2-methyl-3,4,6,-trifluorobenzoylacetate, ethyl orthoformate, acetic anhydride and 3-amino-1,2,5-thiadiazole hydrochloride.