참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethanone, 1-(2,3-dihydro-5-nitro-1H-indol-1-yl)- | HCID 36566 | — |
| 생성물 | 1-Ethyl-5-nitro-indoline | HCID 23499145 | 109.4% |
반응 단계
1-Acetyl-5-nitro-indoline (1.00 g, 4.85 mmol) was added to borane-THF complex 1M, 10 mL, 10 mmol). The mixture was heated at reflux for 4 h. With ice-water bath cooling, the mixture was slowly reated with 6N HCl (4 mL). Then the mixture was heated at 50° C. for 1 h. The organic solvent was evaporated off and the resulting suspension was filtered to give an orange solid (1.02 g) which was washed with water: mp 97°-98° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05866579 |
|---|
| 출처 데이터셋 | uspto-grants-1999_02 |
|---|
| ORD ID | ord-cae08d09cb174c56a3c433fba5933db8 |
|---|
| 출처 메모 | uspto-grants-1999_02 |
|---|
