N-heptylacetamide → 1-Heptanamine, N-ethyl-

HRID 36145

반응식

HRID 36145 반응식
[CH2:1]([NH:8][C:9](=O)[CH3:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[H-].[Al+3].[Li+].[H-].[H-].[H-].O.[OH-].[Na+]>C(OCC)C>[CH2:1]([NH:8][CH2:9][CH3:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

참가 물질

5

반응물 3

HCID 347488N-heptylacetamideHCID 21226445Aluminium lithium hydrideHCID 23719242Sodium hydroxide--water (1/1/1)

생성물 1

HCID 480381-Heptanamine, N-ethyl-

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

A mixture of a solution of 5.5 gms of the N-heptylacetamide in 150 ml of diethyl ether and 3.99 gms of lithium aluminum hydride are stirred at room temperature for 18 hours. The reaction mixture is then worked up with H2O/NaOH by the Fieser method, following which the organic layer is dried over MgSO4, filtered, and concentrated under vacuum to give N-heptyl-N-ethylamine.

후처리

  1. dry with materialis dried over MgSO4
  2. filtrationfiltered
  3. concentrationconcentrated under vacuum

출처 및 근거

ORD 기록
ord-f3528eb525984558858b648e2ac6c3f7
출처 데이터셋
uspto-grants-1995_05
특허 번호
US05412137

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