Sarcosine → 6-[(Carboxymethyl)amino]hexanoic acid

반응식

Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8].C[NH:12][CH2:13][C:14]([OH:16])=[O:15].[H-].[Na+]>>[C:14]([CH2:13][NH:12][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8])([OH:16])=[O:15]

참가 물질

반응물 3

HCID 1088Sarcosine

HCID 24758Sodium hydride

HCID 4170292Methyl 6-Bromohexanoate

생성물 1

HCID 543345866-[(Carboxymethyl)amino]hexanoic acid

실험 절차

In this reaction scheme, methyl 6-bromohexanoate is alkylated with methyl glycine in the presence of sodium hydride to afford the 6-[(carboxymethyl)amino]hexanoic acid. Treatment of 6-[(carboxymethyl)amino]hexanoic acid with sodium hydroxide affords the corresponding 6-[(carboxymethyl)amino]hexanoic acid disodium salt.

출처 및 근거

ORD 기록: ord-1115f63737674e86ba475dd5b5e8555d
출처 데이터셋: uspto-grants-1999_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05869527

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