4-(Benzyloxy)phenyl benzoate → p-Hydroxyphenyl benzoate

HRID 363089

반응식

HRID 363089 반응식
[C:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([O:16]CC2C=CC=CC=2)=[CH:12][CH:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H][H]>[C].[Pd].C(O)C>[C:1]([O:9][C:10]1[CH:11]=[CH:12][C:13]([OH:16])=[CH:14][CH:15]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

5

반응물 2

HCID 2412554-(Benzyloxy)phenyl benzoateHCID 178418361HCID 178418361, 화합물2회

생성물 1

HCID 75549p-Hydroxyphenyl benzoate수율 94%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

A reaction vessel was charged with 38 g of 4-benzyloxyphenyl benzoate and 500 ml of ethanol, and the air in the vessel was replaced with nitrogen. Then, 1.0 g of 10% palladium carbon was added thereto, and the nitrogen in the vessel was replaced with hydrogen, followed by vigorous stirring at room temperature for 24 hours. The hydrogen in the vessel was replaced with nitrogen, after which the reaction mixture was filtered though celite, and the filtrate was concentrated, which afforded 24.5 g of 4-hydroxyphenyl benzoate (94% yield).

후처리

  1. filtrationafter which the reaction mixture was filtered though celite
  2. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-a929d519d72544c49f384c6363083c0c
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05872137

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