Water → 6-Phenylnicotinic acid

HRID 363184

반응식

HRID 363184 반응식
[C:1]1([C:7]2[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Mn]([O-])(=O)(=O)=[O:15].[K+].[OH2:20]>>[C:1]1([C:7]2[CH:12]=[CH:11][C:10]([C:13]([OH:15])=[O:20])=[CH:9][N:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 962WaterHCID 474675-Methyl-2-phenylpyridineHCID 516875Potassium Permanganate

생성물 1

HCID 1201186-Phenylnicotinic acid

실험 절차

A suspension of 2-phenyl-5-methyl pyridine (1.03 g, 6.09 mmol) and potassium permanganate (2.89 g, 18.3 mmol), in water (25 mL) was heated at reflux for 2 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (1 mL) was added to the colourless filtrate and the product was collected as a white solid by filtration.

후처리

  1. temperatureat reflux for 2 hours
  2. filtrationfiltered through celite
  3. customto remove the solids
  4. additionAcetic acid (1 mL) was added to the colourless filtrate
  5. filtrationthe product was collected as a white solid by filtration

출처 및 근거

ORD 기록
ord-6e644e5ebedd4852bf22e76bd7adb84c
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05872136

연결된 노트

불러오는 중…