1-Hydroxybenzotriazole → piperidine N,N-dimethylformamide

HRID 365676

반응식

HRID 365676 반응식
C[CH2:2][N:3]([CH:7](C)C)[CH:4](C)C.[CH:10]1[CH:11]=[CH:12]C2N([OH:19])N=[N:16][C:14]=2[CH:15]=1>CN1CCCC1=O>[NH:16]1[CH2:12][CH2:11][CH2:10][CH2:15][CH2:14]1.[CH3:7][N:3]([CH:2]=[O:19])[CH3:4]

참가 물질

4

반응물 2

HCID 757711-HydroxybenzotriazoleHCID 81531Diisopropylethylamine

생성물 1

HCID 23501187piperidine N,N-dimethylformamide

시약·촉매·용매 1

HCID 13387N-methyl-2-pyrrolidone용매

실험 절차

125 ml of 2.6 g Bop/1-methyl-2-pyrrolidone +1.7 ml of DIEA +0.8 g of HOBt (15 hours, two times)

출처 및 근거

ORD 기록
ord-8aaecd5f6ac64646b1fa047fffa1fc7c
출처 데이터셋
uspto-grants-2000_10
특허 번호
US06127519

연결된 노트

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