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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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Heptanedinitrile → 2-Aminocyclohex-1-ene-1-carbonitrile

HRID 366399
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HRID 366399 반응식
[C:1]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]#[N:9])#[N:2].[H-].[Na+]>O>[NH2:2][C:1]1[CH2:3][CH2:4][CH2:5][CH2:6][C:7]=1[C:8]#[N:9]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

4

반응물 2

HCID 12590HeptanedinitrileHCID 24758Sodium hydride

생성물 1

HCID 2901752-Aminocyclohex-1-ene-1-carbonitrile

시약·촉매·용매 1

HCID 962Water용매

실험 절차

1,5-Dicyanopentane (Aldrich Chemicals) (25.0 g, 205 mmol), sodium hydride (60% oil dispersion; 8.2 g, 205 mmol) and T.H.F. (150 ml) were heated under reflux for 17 hours. After cooling, water (150 ml) was added and the upper organic layer removed, dried (Na2SO4) filtered and the solvent evaporated. Recrystallisation from hot toluene (80° C.) gave the product as beige crystals.

후처리

  1. temperature(150 ml) were heated
  2. temperatureunder reflux for 17 hours
  3. temperatureAfter cooling
  4. customthe upper organic layer removed
  5. dry with materialdried (Na2SO4)
  6. filtrationfiltered
  7. customthe solvent evaporated
  8. customRecrystallisation from hot toluene (80° C.)

출처 및 근거

ORD 기록
ord-c54ede75b2ad4a5c849208ca430985ff
출처 데이터셋
uspto-grants-2000_10
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US06130228

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