2-Bromo-1-(4-hydroxyphenyl)ethanone → 4-(2-Methylthiazol-4-yl)-phenol hydrobromide

HRID 366450노트

반응식

HRID 366450 반응식
[CH:1]1[C:6]([C:7]([CH2:9][Br:10])=O)=[CH:5][CH:4]=[C:3]([OH:11])[CH:2]=1.[C:12]([NH2:15])(=[S:14])[CH3:13]>C(Cl)Cl>[BrH:10].[CH3:13][C:12]1[S:14][CH:9]=[C:7]([C:6]2[CH:5]=[CH:4][C:3]([OH:11])=[CH:2][CH:1]=2)[N:15]=1

참가 물질

4

반응물 2

HCID 49642-Bromo-1-(4-hydroxyphenyl)ethanoneHCID 2723949Thioacetamide

생성물 1

HCID 232892844-(2-Methylthiazol-4-yl)-phenol hydrobromide

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

4-(2-Methylthiazol-4-yl)-phenol hydrobromide was prepared from α-bromo-4-hydroxyacetophenone and thioacetamide as described in Preparation 48; m.p. 250-251° C. (CH2Cl2).

후처리

  1. customas described in Preparation 48

출처 및 근거

ORD 기록
ord-a6c7b88a312e456890a5990db3de5b79
출처 데이터셋
uspto-grants-2000_10
특허 번호
US06130217

반응 노트

불러오는 중…