Ethyl chloroformate → Ethyl 2,2-dimethoxyethylcarbamate
반응식
Cl[C:2]([O:4][CH2:5][CH3:6])=[O:3].[CH3:7][O:8][CH:9]([O:12][CH3:13])[CH2:10][NH2:11].[OH-].[Na+]>C1(C)C=CC=CC=1.O>[CH3:7][O:8][CH:9]([O:12][CH3:13])[CH2:10][NH:11][C:2](=[O:3])[O:4][CH2:5][CH3:6]참가 물질
6
실험 절차
214 g (2 mol) of ethyl chloroformate are added dropwise to 214 g (2 mol) of aminoacetaldehyde dimethyl acetal in 1 l of toluene and 90 g of NaOH in 500 ml of water at 10° C. The mixture is stirred at room temperature for a further 2 hours and the aqueous phase is separated off, saturated with sodium chloride and extracted with toluene. The toluene solutions are dried over magnesium sulphate and concentrated and the residue is distilled.
후처리
- customthe aqueous phase is separated off, saturated with sodium chloride
- extractionextracted with toluene
- dry with materialThe toluene solutions are dried over magnesium sulphate
- concentrationconcentrated
- distillationthe residue is distilled
출처 및 근거
- ORD 기록
- ord-9d97b7ac3ac0435c8feda74e2c76dc3b
- 출처 데이터셋
- uspto-grants-1995_05
- 특허 번호
- US05416096
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