Ethyl Acetoacetate → Ethyl 3-Hydroxybutyrate
반응식
[O:1]=[C:2]([CH3:9])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5]>CO.O>[OH:1][CH:2]([CH3:9])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5]참가 물질
3
실험 절차
The same procedure of Example 5 is repeated with the only differences that 1.95 g of ethyl 3-oxo-butyrate were weighed and dissolved in MeOH/H2O 19/1 (v/v) and the catalyst of Example 15 was utilized. At the end of the reaction, the ethyl 3-hydroxybutyrate resulted to be equal to 91%, while the ethyl 3-dimetoxybutyrate resulted equal to 9%. The stereoinduction was >99% in favour of the antipode (S).
후처리
- customAt the end of the reaction
출처 및 근거
- ORD 기록
- ord-06436ccc24a740108351f3988fd3e4b7
- 출처 데이터셋
- uspto-grants-2000_10
- 특허 번호
- US06133191
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