p-Anisoyl chloride → HCID 23288165, 화합물

반응식

[CH3:1][N:2]1[CH2:7][CH:6]=[C:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[NH:10][CH:9]=2)[CH2:4][CH2:3]1.[CH3:17][O:18][C:19]1[CH:27]=[CH:26][C:22]([C:23](Cl)=[O:24])=[CH:21][CH:20]=1>>[CH3:17][O:18][C:19]1[CH:27]=[CH:26][C:22]([C:23]([N:10]2[C:11]3[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=3)[C:8]([C:5]3[CH2:4][CH2:3][N:2]([CH3:1])[CH2:7][CH:6]=3)=[CH:9]2)=[O:24])=[CH:21][CH:20]=1

참가 물질

반응물 2

HCID 7477p-Anisoyl chloride

HCID 1522153-(1-Methyl-1,2,3,6-tetrahydropyrid-4-yl)indole

생성물 1

HCID 23288165HCID 23288165, 화합물

실험 절차

(10.9 mg, 27%); from 3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (Example 4e, 24.8 mg, 0.12 mmol) and 4-methoxybenzoyl chloride (35 uL, 0.24 mmol); HRMS-FAB+ for C22H22N2O2 : calculated MH+ : 347.17596; found: 347.17819.

출처 및 근거

ORD 기록: ord-219f4c5ef9994719915c93d457ab1e1a
출처 데이터셋: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06133287

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