p-Anisoyl chloride → HCID 23288103, 화합물

반응식

[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]3[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH:16]=3)=[CH:7][NH:8]2)=[CH:4][CH:3]=1.[CH3:18][O:19][C:20]1[CH:28]=[CH:27][C:23]([C:24](Cl)=[O:25])=[CH:22][CH:21]=1>>[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]3[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH:16]=3)=[CH:7][N:8]2[C:24](=[O:25])[C:23]2[CH:27]=[CH:28][C:20]([O:19][CH3:18])=[CH:21][CH:22]=2)=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 7477p-Anisoyl chloride

HCID 232881216-Bromo-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

생성물 1

HCID 23288103HCID 23288103, 화합물

실험 절차

(17.4 mg, 48%); from 6-bromo-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (Example 4f, 25.0 mg, 0.086 mmol) and 4-methoxybenzoyl chloride (26 uL, 0.17 mmol); HRMS-FAB+ for C22H21O2N2Br, calculated MH+ : 425.08646; found: 425.08292.

출처 및 근거

ORD 기록: ord-009dd6ebdff9414296adcd99deb14db0
출처 데이터셋: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06133287

반응 노트

불러오는 중…