Hydroxyamine hydrochloride → HCID 178513387, 화합물
반응식
[ClH:1].[NH2:2][OH:3].C[O-].[Na+].Cl[C:8]1[CH:9]=[C:10]([C:15]#[N:16])[CH:11]=[N:12][C:13]=1[Cl:14]>CO>[Cl:1][C:8]1[CH:9]=[C:10]([C:15](=[NH:16])[NH:2][OH:3])[CH:11]=[N:12][C:13]=1[Cl:14]참가 물질
5
실험 절차
Hydroxylamine hydrochloride (2.6 g, 0.038 mol) was slurried in methanol (75 mL) and sodium methoxide (2.0 g, 0.037 mol) added. The mixture was stirred for half an hour and 5,6-dichloro-3-pyridinecarbonitrile (4.3 g, 0.025 mol) added. The mixture was stirred at room temperature overnight and filtered. The precipitate was washed with water and methanol and dried to give the desired product (4.2 g, 82%) as a white solid, MP 182-184° C.
후처리
- stirringThe mixture was stirred at room temperature overnight
- filtrationfiltered
- washThe precipitate was washed with water and methanol
- customdried
출처 및 근거
- ORD 기록
- ord-ec543ccb5e3a4768bbdce4c8798977de
- 출처 데이터셋
- uspto-grants-2000_10
- 특허 번호
- US06133294
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