Methyl iodide → HCID 18630005, 화합물

반응식

[CH2:1]([N:3]([CH2:16][O:17][CH3:18])[C:4](=[O:15])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Si:11]([CH3:14])([CH3:13])[CH3:12])[CH3:2].[CH3:19]I>>[CH2:1]([N:3]([CH2:16][O:17][CH3:18])[C:4](=[O:15])[C:5]1[C:6]([Si:11]([CH3:13])([CH3:12])[CH3:14])=[CH:7][CH:8]=[CH:9][C:10]=1[CH3:19])[CH3:2]

참가 물질

반응물 2

HCID 6328Methyl iodide

HCID 18630303HCID 18630303, 화합물

생성물 1

HCID 18630005HCID 18630005, 화합물

실험 절차

The compound of Example 50 (1.33 g, 5.0 mmol) and MeI (2.8 g, 20 mmol) were combined according to General Method B. The resulting reaction was partitioned between ethyl acetate and sat aq NaHCO3. The organic phase was washed with brine, dried (MgSO4), and concentrated to afford a quantitative yield of the title compound as an oil.

후처리

customThe resulting reaction
customwas partitioned between ethyl acetate
washThe organic phase was washed with brine
dry with materialdried (MgSO4)
concentrationconcentrated

출처 및 근거

ORD 기록: ord-0d1400b3fa674b63a339220629478a68
출처 데이터셋: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06133252

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