Ethoxyethylamine → N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide
반응식
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Si:11]([CH3:14])([CH3:13])[CH3:12])[C:3]=1[C:4](Cl)=[O:5].[CH2:15]([O:17][CH2:18][CH2:19][NH2:20])[CH3:16]>C1(C)C=CC=CC=1>[CH2:15]([O:17][CH2:18][CH2:19][NH:20][C:4](=[O:5])[C:3]1[C:7]([Si:11]([CH3:14])([CH3:13])[CH3:12])=[CH:8][CH:9]=[CH:10][C:2]=1[Cl:1])[CH3:16]참가 물질
4
실험 절차
The compound of Example b (4.94 g, 20 mmol), 2-ethoxyethyl amine (3.92 g, 44 mmol), and toluene (35 mL) were combined according to General Method E1. The crude product was recrystallized from aq ethanol to afford 3.97 g of N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide as white solid, a 66% yield. m.p. 71-73° C.
후처리
- customThe crude product was recrystallized from aq ethanol
출처 및 근거
- ORD 기록
- ord-7c7469ef38f34e528b1eecd2407de8d7
- 출처 데이터셋
- uspto-grants-2000_10
- 특허 번호
- US06133252
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