Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → N-[1,1-dimethoxycarbonyl-4-oxo-4-(2-thienyl)butyl]-L-alanyl-L-proline trifluoroacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | N-[1,1-dimethoxycarbonyl-4-oxo-4-(2-thienyl)butyl]-L-alanyl-L-proline t-butyl ester | HCID 70443263 | — |
| 생성물 | N-[1,1-dimethoxycarbonyl-4-oxo-4-(2-thienyl)butyl]-L-alanyl-L-proline trifluoroacetate | HCID 70443432 | — |
반응 단계
A mixture of N-[1,1-dimethoxycarbonyl-4-oxo-4-(2-thienyl)butyl]-L-alanyl-L-proline t-butyl ester (Example 31; 1.5 g.) and trifluoroacetic acid (20 ml.) was kept at laboratory temperature for 2 hours and then evaporated to dryness under reduced pressure at less than 30° C., using toluene as described in Example 20. There was thus obtained as an oil N-[1,1-dimethoxycarbonyl-4-oxo-4-(2-thienyl)butyl]-L-alanyl-L-proline trifluoroacetate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04528282 |
| 출처 데이터셋 | uspto-grants-1985_07 |
| ORD ID | ord-e3fc204a01a2451e899de03e7dacaae9 |
| 출처 메모 | uspto-grants-1985_07 |