Diethyl Oxalate → 1-Ethyl-2,3-piperazinedione
반응식
CCO[C:4]([C:6]([O:8]CC)=O)=[O:5].[CH2:11]([NH:13][CH2:14][CH2:15][NH2:16])[CH3:12]>C(O)C>[CH2:11]([N:13]1[CH2:14][CH2:15][NH:16][C:6](=[O:8])[C:4]1=[O:5])[CH3:12]참가 물질
4
실험 절차
Into a mixture comprising 8 g of a diethyl ester of oxalic acid and 8 ml of ethanol was dropped at room temperature 4.4 g of N-ethyl ethylenediamine. The resulting mixture was allowed to react for 3 hours, and then heated to remove the ethanol. Subsequently, the residue was recrystallized from 10 ml of dioxane to obtain 5.4 g of 1-ethyl-2,3-dioxo-piperazine, m.p. 124° C, yield 76.0%.
후처리
- customto react for 3 hours
- temperatureheated
- customto remove the ethanol
- customSubsequently, the residue was recrystallized from 10 ml of dioxane
출처 및 근거
- ORD 기록
- ord-933aa54376704b39bf9a3efd64b9693c
- 출처 데이터셋
- uspto-grants-1978_05
- 특허 번호
- US04087424
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