Cyclohexylamine → HCID 18756975, 화합물

HRID 371699

반응식

HRID 371699 반응식
[CH:1]1([NH2:7])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:8]([CH2:11][P:12](=[O:17])([O:15]C)[O:13]C)(O)=[O:9].C1(N=C=NC2CCCCC2)CCCCC1>C(Cl)Cl>[CH:1]1([NH:7][C:8]([CH2:11][P:12](=[O:13])([OH:17])[OH:15])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

5

반응물 3

HCID 7965CyclohexylamineHCID 10868DicyclohexylcarbodiimideHCID 1899642-(Dimethoxyphosphoryl)acetic acid

생성물 1

HCID 18756975HCID 18756975, 화합물수율 57%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Cyclohexyl amine (0.045 mole) and dimethyl (carboxymethyl)phosphonate (0.04 mole) were dissolved in 100 ml. of methylene chloride. As the solution was stirred, dicyclohexylcarbodiimide (0.045 mole) was added portionwise. The solution was stirred overnight and the mixture filtered. The filtrate was concentrated to a solid and the solid recrystallized from an appropriate solvent such as methanol. m.p. 180°-3° C.; yield 57%.

후처리

  1. stirringThe solution was stirred overnight
  2. filtrationthe mixture filtered
  3. concentrationThe filtrate was concentrated to a solid
  4. customthe solid recrystallized from an appropriate solvent such as methanol

출처 및 근거

ORD 기록
ord-fa57d76245684623a517de4b633bf7ab
출처 데이터셋
uspto-grants-1978_05
특허 번호
US04087522

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