Hydrochloric Acid → HCID 178479019, 화합물

HRID 371886노트

반응식

[NH2:1][C:2]1[C:16]([Br:17])=[CH:15][C:14]([C:18]([O:20]CC)=[O:19])=[CH:13][C:3]=1[CH2:4][NH:5][C@H:6]1[CH2:11][CH2:10][C@H:9]([OH:12])[CH2:8][CH2:7]1.[ClH:23]>>[ClH:23].[NH2:1][C:2]1[C:16]([Br:17])=[CH:15][C:14]([C:18]([OH:20])=[O:19])=[CH:13][C:3]=1[CH2:4][NH:5][C@H:6]1[CH2:7][CH2:8][C@H:9]([OH:12])[CH2:10][CH2:11]1

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 178468565HCID 178468565, 화합물

생성물 1

HCID 178479019HCID 178479019, 화합물

실험 절차

2-Amino-3-bromo-5-carboxy-N-(trans-4'-hydroxy-cyclohexyl)-benzylamine hydrochloride, m.p. 279° C (decomp.) was prepared from 2-amino-3-bromo-5-carbethoxy-N-(trans-4'-hydroxy-cyclohexyl)-benzylamine and 6 N hydrochloric acid analogous to Example 272.

출처 및 근거

ORD 기록: ord-f6f22170d5ad493e9b9c95c2db6300b2
출처 데이터셋: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: USRE029628

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