Hydrogen Peroxide → HCID 20354850, 화합물

HRID 372122노트

반응식

HRID 372122 반응식
[C:1]([O:4][CH:5]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:6][CH2:7][C:8]1[C:9](=[O:13])[CH2:10][CH2:11][CH:12]=1)(=[O:3])[CH3:2].[OH:19]O.[OH-].[Na+]>CO>[C:1]([O:4][CH:5]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:6][CH2:7][C:8]12[O:19][CH:12]1[CH2:11][CH2:10][C:9]2=[O:13])(=[O:3])[CH3:2]

참가 물질

5

반응물 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 20354852HCID 20354852, 화합물

생성물 1

HCID 20354850HCID 20354850, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A stirred solution of 2-(3-acetoxyoctyl)cyclopent-2-enone (31.8 g.) [prepared as described in (f) above] in methanol (700 ml.) was treated slowly with aqueous hydrogen peroxide solution (45 ml. of "100 vol." solution) and aqueous 4N sodium hydroxide solution (15 ml.) at 5° to 10° C. and allowed to stand at room temperature for 18 hours. The solution was concentrated in vacuo (to about 100 ml. volume), and water (100 ml.) was added to the residue. The mixture was extracted with chloroform and the chloroform extract was washed with water and dried over magnesium sulphate. The solvent was removed in vacuo to give 2-(3-acetoxyoctyl)-2,3-epoxycyclopentanone (26.4 g.) which was used as starting material in the following preparation (h) of 5-acetoxy-2-(3-acetoxyoctyl)cyclopent-2-enone without further purification.

후처리

  1. concentrationThe solution was concentrated in vacuo (to about 100 ml. volume), and water (100 ml.)
  2. additionwas added to the residue
  3. extractionThe mixture was extracted with chloroform
  4. extractionthe chloroform extract
  5. washwas washed with water
  6. dry with materialdried over magnesium sulphate
  7. customThe solvent was removed in vacuo

출처 및 근거

ORD 기록
ord-6ee7b2341032409fbb294ac5c677e50d
출처 데이터셋
uspto-grants-1978_05
특허 번호
US04088821

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