O-Cresol → HCID 54096441, 화합물

HRID 372160

반응식

HRID 372160 반응식
[CH3:1][NH:2][C:3]([NH:5][CH3:6])=[O:4].C/[C:8](/[C:14]([O-:16])=O)=[C:9](\C)/[C:10]([O-:12])=[O:11].[C:17]1(C)C(O)=CC=CC=1>ClC1C=CC=CC=1Cl>[CH3:1][N:2]1[C:8](=[CH:9][C:10]([O:12][CH3:17])=[O:11])[C:14](=[O:16])[N:5]([CH3:6])[C:3]1=[O:4]

참가 물질

5

반응물 3

HCID 335O-CresolHCID 7293N,N'-DimethylureaHCID 5459894Dimethylmaleate

생성물 1

HCID 54096441HCID 54096441, 화합물

시약·촉매·용매 1

HCID 72391,2-Dichlorobenzene용매

실험 절차

44 g of N,N'-dimethylurea were dissolved in 150 g of o-dichlorobenzene and reacted with 72 g of dimethylmaleate for 2 hours at 180°-185° C after the addition of 25 g of cresol. The solvent was removed from this reaction mixture and the residue was fractionated under vacuum, 85 g (= 85% of the theory) of the desired product distilling over at 0.07 Torr and 128° C. A purified product melting at 49.5° C could be obtained by dissolving the crude product in chloroform and reprecipitating it with ether. The structure of the purified product was confirmed by IR and NMR spectra and by elementary analysis.

후처리

  1. customThe solvent was removed from this reaction mixture
  2. distillationdistilling over at 0.07 Torr and 128° C

출처 및 근거

ORD 기록
ord-57af96b92cdb484db5e792ce9ad2d545
출처 데이터셋
uspto-grants-1978_05
특허 번호
US04089860

연결된 노트

불러오는 중…