Hydrochloric Acid → HCID 70620434, 화합물

HRID 372777노트

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HRID 372777 반응식
C(OC([NH:8][C@H:9]([C:18]([NH:20][CH2:21][C:22]([NH:24][CH2:25][C:26]([NH:28][C@H:29]([C:40]([NH:42][C@H:43]([C:48]([OH:50])=[O:49])[CH2:44][CH2:45][S:46][CH3:47])=[O:41])[CH2:30][C:31]1[C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[NH:33][CH:32]=1)=[O:27])=[O:23])=[O:19])[CH2:10][C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)=O)(C)(C)C.[ClH:51]>O1CCOCC1>[ClH:51].[NH2:8][C@H:9]([C:18]([NH:20][CH2:21][C:22]([NH:24][CH2:25][C:26]([NH:28][C@H:29]([C:40]([NH:42][C@H:43]([C:48]([OH:50])=[O:49])[CH2:44][CH2:45][S:46][CH3:47])=[O:41])[CH2:30][C:31]1[C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[NH:33][CH:32]=1)=[O:27])=[O:23])=[O:19])[CH2:10][C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 54048888HCID 54048888, 화합물

생성물 1

HCID 70620434HCID 70620434, 화합물

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

The N-t-butoxycarbonyl-L-tyrosylglycylglycyl-L-tryptophyl-L-methionine is dissolved in 100 parts dioxane and stirred with a ten-fold excess of 2 N hydrochloric acid at room temperature for 15 minutes. The solvent is then removed under reduced pressure and the residue is triturated with ethyl ether. The resulting solid is precipitated from the mixture of methanol and ether to afford L-tyrosylglycylglycyl-L-tryptophyl-L-methionine hydrochloride. This compound is represented by the following formula

후처리

  1. customThe solvent is then removed under reduced pressure
  2. customthe residue is triturated with ethyl ether
  3. customThe resulting solid is precipitated from the mixture of methanol and ether

출처 및 근거

ORD 기록
ord-3bae411051c84cdba4204a9f6b597017
출처 데이터셋
uspto-grants-1978_05
특허 번호
US04092304

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