Acetic Anhydride → Ethanone, 1-(2,3-dihydro-5-nitro-1H-indol-1-yl)-

HRID 373722

반응식

HRID 373722 반응식
[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][CH2:8][CH2:7]2)([O-:3])=[O:2].[C:13](OC(=O)C)(=[O:15])[CH3:14]>N1C=CC=CC=1>[C:13]([N:9]1[C:10]2[C:6](=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:12][CH:11]=2)[CH2:7][CH2:8]1)(=[O:15])[CH3:14]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 362195-Nitroindoline

생성물 1

HCID 36566Ethanone, 1-(2,3-dihydro-5-nitro-1H-indol-1-yl)-

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

A mixture of 5-nitroindoline (I, 12.012 g) in pyridine (100 ml) and acetic anhydride (50 ml) is stirred for 17 hr under argon. The mixture is then concentrated under reduced pressure to give the title compound, mp 175°-177°; NMR (CDCl3, 300 MHz) 8.28, 8.10, 8.01, 4.23, 3.31 and 2.28 δ; CMR (CDCl3, 75.47 MHz) 23.95, 27.01, 49.11, 115.73, 119.93, 124.27, 132.4, 143.4 and 169.8 δ; IR (CHCl3) 1680, 1600, 1480, 1470, 1390, 1340 and 1320 cm-1.

후처리

  1. concentrationThe mixture is then concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-57c24998a7c149c5b442486e85778aa5
출처 데이터셋
uspto-grants-1992_11
특허 번호
US05164510

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