m-Chloroperbenzoic acid → 4-(4-(2-Quinolinylmethylsulfinyl)styryl)benzoic acid

HRID 373949

반응식

HRID 373949 반응식
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][S:12][C:13]1[CH:29]=[CH:28][C:16]([CH:17]=[CH:18][C:19]2[CH:27]=[CH:26][C:22]([C:23]([OH:25])=[O:24])=[CH:21][CH:20]=2)=[CH:15][CH:14]=1.ClC1C=CC=C(C(OO)=[O:38])C=1.C(=O)([O-])O.[K+]>ClC=CCl>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][S:12]([C:13]1[CH:29]=[CH:28][C:16]([CH:17]=[CH:18][C:19]2[CH:20]=[CH:21][C:22]([C:23]([OH:25])=[O:24])=[CH:26][CH:27]=2)=[CH:15][CH:14]=1)=[O:38]

참가 물질

5

반응물 3

HCID 70297m-Chloroperbenzoic acidHCID 516893Potassium BicarbonateHCID 541560444-(4-(2-Quinolinylmethylthio)styryl)benzoic acid

생성물 1

HCID 545127564-(4-(2-Quinolinylmethylsulfinyl)styryl)benzoic acid

시약·촉매·용매 1

HCID 109001,2-Dichloroethylene용매

실험 절차

4-(4-(2-quinolinylmethylthio)styryl)benzoic acid (4 mmol) in dichloroethene (50 ml) is stirred with m-chloroperbenzoic acid (4 mmol) and solid potassium hydrogen carbonate (1.0 g). The reaction is assayed by TLC and upon consumption of the starting thio compound, the mixture is filtered, washed with dilute aqueous sodium bisulfite, dried and evaporated to give 4-(4-(2-quinolinylmethylsulfinyl)styryl)benzoic acid.

후처리

  1. customThe reaction is assayed by TLC and upon consumption of the starting thio compound
  2. filtrationthe mixture is filtered
  3. washwashed with dilute aqueous sodium bisulfite
  4. customdried
  5. customevaporated

출처 및 근거

ORD 기록
ord-466eee6c7a1d4223bdf708061fca70b3
출처 데이터셋
uspto-grants-1992_11
특허 번호
US05166210

연결된 노트

불러오는 중…