Hydrogen Bromide → 3-(3-Bromopropyl)pyridine

반응식

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][CH2:9]O)[CH:2]=1.[BrH:11]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][CH2:9][Br:11])[CH:2]=1

참가 물질

반응물 2

HCID 260Hydrogen Bromide

HCID 178613-Pyridinepropanol

생성물 1

HCID 127015683-(3-Bromopropyl)pyridine

실험 절차

To 17.0 g (124 moles) of 3-(3-pyridyl)-1-propanol was added 240 mL of 48% hydrobromic acid. The mixture was heated under reflux for 4 hours, and then evaporated to dryness to afford the hydrobromide salt of 3-(3-pyridyl)-1-bromopropane as an oil in quantitative yield.

후처리

temperatureThe mixture was heated
temperatureunder reflux for 4 hours
customevaporated to dryness

출처 및 근거

ORD 기록: ord-d62f1374cf5c45a8a395275ffd52cb2d
출처 데이터셋: uspto-grants-1996_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05480892

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