Trifluoroacetic acid → Caprine
반응식
C([O:5][C:6](=[O:13])[C@H:7]([CH2:9][CH2:10][CH2:11][CH3:12])[NH2:8])(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[NH2:8][C@H:7]([C:6]([OH:13])=[O:5])[CH2:9][CH2:10][CH2:11][CH3:12]참가 물질
4
실험 절차
23.5 mg of L-N-[(2R or S)-5-ethylthio-2-(1-naphthylmethyl)pentanoyl]norleucine tert-butyl ester was dissolved in 0.2 ml of dichloromethane, and 0.1 ml of trifluoro acetic acid was added thereto. The mixture was stirred at room temperature for four hours. Then, the reaction solution was concentrated under reduced pressure to obtain 20.7 mg of L-N-[(2R or S)-5-ethylthio-2-(1-naphthylmethyl)pentanoyl]norleucine as colorless solid.
후처리
- concentrationThen, the reaction solution was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-aa312e5f1bd544c6952f2a6f19a3f20f
- 출처 데이터셋
- uspto-grants-1996_01
- 특허 번호
- US05481036
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