Thionyl Chloride → 3-(3-Fluorophenyl)propanoyl chloride

HRID 375597

반응식

HRID 375597 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[CH2:5][CH2:6][C:7](O)=[O:8].S(Cl)([Cl:15])=O>>[F:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[CH2:5][CH2:6][C:7]([Cl:15])=[O:8]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 27374893-(3-Fluorophenyl)propionic acid

생성물 1

HCID 189935013-(3-Fluorophenyl)propanoyl chloride

실험 절차

A solution of 3-fluorohydrocinnamic acid (28 g) in thionyl chloride (90 ml) was heated at reflux for 3 hours. 3-Fluorohydrocinnamoyl chloride (27 g) was isolated by distillation (150°-110° C. @ ca 20 mm.Hg).

후처리

  1. temperatureat reflux for 3 hours

출처 및 근거

ORD 기록
ord-66e7a4465c454ece8d230e1ae0a91cbd
출처 데이터셋
uspto-grants-1996_01
특허 번호
US05486541

연결된 노트

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