Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-(1H-Indol-7-YL)propanenitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 반응물 | Benzoic acid, 3-methyl-2-nitro-, methyl ester | HCID 79621 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-(1H-Indol-7-YL)propanenitrile | HCID 19959105 | — |
반응 단계
A solution of methyl 3-methyl-2-nitrobenzoate (43 g, 0.22 mole), dimethylformamide dimethyl acetal (52.5 g, 0.44 mole) and piperidine (18.7 g, 0.22 mole) in dimethylformamide (120 ml) is heated under reflux for 24 hours, cooled and poured into water to give the crude product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05486612 |
| 출처 데이터셋 | uspto-grants-1996_01 |
| ORD ID | ord-99b69e106a784f89aab343a351df0e89 |
| 출처 메모 | uspto-grants-1996_01 |