Cyanuric chloride → 4,6-dichloro-2-ethoxycarbonylmethylamino-S-triazine

HRID 375772

반응식

HRID 375772 반응식
[N:1]1[C:8]([Cl:9])=[N:7][C:5](Cl)=[N:4][C:2]=1[Cl:3].Cl.[NH2:11][CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14].C(=O)(O)[O-].[Na+]>O1CCOCC1>[Cl:9][C:8]1[N:1]=[C:2]([Cl:3])[N:4]=[C:5]([NH:11][CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:7]=1

참가 물질

5

반응물 3

HCID 7954Cyanuric chlorideHCID 516892Sodium BicarbonateHCID 2723640Glycine ethyl ester, hydrochloride

생성물 1

HCID 147462614,6-dichloro-2-ethoxycarbonylmethylamino-S-triazine

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

36.9 g of cyanuric chloride, 27.9 g of ethyl glycinate hydrochloride and 33.6 g of sodium bicarbonate were heated under reflux in 200 ml of dioxane for 30 minutes. At the end of this time, the dioxane was removed by distillation under reduced pressure, and a mixture of ethyl acetate and water was added to the resulting residue, after which the mixture was shaken.

후처리

  1. customAt the end of this time, the dioxane was removed by distillation under reduced pressure
  2. additiona mixture of ethyl acetate and water
  3. additionwas added to the resulting residue

출처 및 근거

ORD 기록
ord-bd7a9204833e44b8adfa2e160635c080
출처 데이터셋
uspto-grants-1996_01
특허 번호
US05486556

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