m-Chloroperbenzoic acid → HCID 19361778, 화합물
반응식
ClC1C=CC=C(C(OO)=[O:9])C=1.[O:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[N:18]=1>C(Cl)(Cl)Cl>[O:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[N+:18]=1[O-:9]참가 물질
4
반응 조건
- 온도
- 0 °C
실험 절차
4.90 g of metachioroperbenzoic acid are added in portions to a solution of 2.20 g of 2-furan-2-yl-6-methylpyridine (13.8 mmol) in 50 ml of chloroform cooled to 0° C. The mixture is stirred for 12 hours at room temperature and then the precipitate is removed by filtration and the filtrate is washed with a 5% aqueous solution of sodium bicarbonate. After drying over magnesium sulfate, filtration and evaporation, the title product is isolated by chromatography on a silica column (eluent: chloroform/methanol; 99:1). 1.25 g of a white powder are recovered.