Triphenylstannane → 3-triphenylstannylpropanenitrile

HRID 376829

반응식

HRID 376829 반응식
[C:1]1([SnH:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:20](#[N:23])[CH:21]=[CH2:22].N(C(C)(C)C#N)=NC(C)(C)C#N>C1(C)C=CC=CC=1>[C:14]1([Sn:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:22][CH2:21][C:20]#[N:23])[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

참가 물질

5

반응물 3

HCID 6460TriphenylstannaneHCID 6547AzobisisobutyronitrileHCID 7855Acrylonitrile

생성물 1

HCID 2897543-triphenylstannylpropanenitrile수율 100%

시약·촉매·용매 1

HCID 1140Toluene용매

반응 조건

온도
60 °C

실험 절차

9.1 g of the triphenyltin hydride (0.026 mol), prepared in the aforementioned example (1), 2.8 g of acrylonitrile (0.052 mol), 85 mg of 2,2'-azobisisobutyronitrile, and 25 ml of toluene were mixed together in a 100 ml four-neck flask equipped with a stirrer and reflux condenser, and stirred while heating for 6 hours at 60° C. After it was confirmed by means of an IR spectrum that the absorption of Sn-H bonds had completely disappeared, a crystal precipitate was separated by filtration. The filtrate was then concentrated under reduced pressure to yield 10.5 g of the final product of 3-(triphenylstannyl)propionitrile (yield=100%).

후처리

  1. additionwere mixed together in a 100 ml four-neck flask
  2. customequipped with a stirrer
  3. temperaturereflux condenser
  4. customAfter it was confirmed by means of an IR spectrum that the absorption of Sn-H bonds
  5. customa crystal precipitate was separated by filtration
  6. concentrationThe filtrate was then concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-9a7777448b394751b5c85b2103e893ee
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06022822

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