Fluorobenzene → HCID 19360812, 화합물

HRID 377061노트

반응식

HRID 377061 반응식
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl-].[Al+3].[Cl-].[Cl-].Cl[CH:13]([CH2:19]Cl)[CH2:14][Si:15]([Cl:18])([Cl:17])[Cl:16]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:19]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[F:1])[CH2:13][CH2:14][Si:15]([Cl:18])([Cl:17])[Cl:16]

참가 물질

4

반응물 3

HCID 10008FluorobenzeneHCID 6451240Aluminum(III) ChlorideHCID 19360815Trichloro(2,3-dichloropropyl)silane

생성물 1

HCID 19360812HCID 19360812, 화합물수율 41%

실험 절차

In the same apparatus and procedures as EXAMPLE 2 above, 18.8 ml (200 mmol) of fluorobenzene and 0.31 g (2.3 mmol) of aluminum chloride were alkylated with 5.61 g (22.8 mmol) of (2,3-dichloropropyl)trichlorosilane for 10 min at 70° C. The aluminum chloride catalyst was quenched with POCl3 and then stirred for another 1 hour to complete the deactivation. Freshly distilled hexane (50 ml) was added to the reaction mixture and insoluble solids in hexane were filtered from the organic soultion. After hexane and fluorobenzene were distilled, the reaction products were vacuum distilled to give 3.39 g of [3,3-bis(fluorophenyl)propyl]trichlorosilane (bp; 121-122° C./0.5 torr, yield; 41%) as a mixutre of isomers.

후처리

  1. customThe aluminum chloride catalyst was quenched with POCl3
  2. additionFreshly distilled hexane (50 ml) was added to the reaction mixture and insoluble solids in hexane
  3. filtrationwere filtered from the organic soultion
  4. distillationAfter hexane and fluorobenzene were distilled
  5. distillationdistilled

출처 및 근거

ORD 기록
ord-1388c80601624ea082e75cff451879fa
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06022987

반응 노트

불러오는 중…