Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(+-)-Methionine → 3'-Hydroxy-[1,1'-biphenyl]-3-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (+-)-Methionine | HCID 876 | — |
| 반응물 | 3'-Methoxy-biphenyl-3-carboxylic acid | HCID 2759550 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Methanesulfonic Acid | HCID 6395 | — |
| 생성물 | 3'-Hydroxy-[1,1'-biphenyl]-3-carboxylic acid | HCID 2759301 | 93.3% |
반응 단계
A suspension of 3'-methoxy-3-biphenylcarboxylic acid (4.1 g) and DL-methionine (26.7 g) in methanesulfonic acid (116 ml) was stirred at room temperature for 22 hours, diluted with water, and extracted three times with diethyl ether. The extracts were combined, washed with brine, dried over magnesium sulfate, and evaporated in vacuo. The residue was crystallized from n-hexane to afford 3'-hydroxy-3-biphenylcarboxylic acid (3.59 g) as a colorless powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06025375 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-912e2197e69c4bb7a28b8e9c6f6a6ac3 |
| 출처 메모 | uspto-grants-2000_02 |