Sodium Hydroxide → Sodium [3-[[2-(4,5-diphenyloxazol-2-yl)-2-cyclopenten-1-yl]methyl]phenoxy]acetate

HRID 377329노트

반응식

HRID 377329 반응식
[C:1]1([C:7]2[N:8]=[C:9]([C:18]3[CH:19]([CH2:23][C:24]4[CH:25]=[C:26]([CH:34]=[CH:35][CH:36]=4)[O:27][CH2:28][C:29]([O:31]CC)=[O:30])[CH2:20][CH2:21][CH:22]=3)[O:10][C:11]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+:38]>C(O)C>[C:1]1([C:7]2[N:8]=[C:9]([C:18]3[CH:19]([CH2:23][C:24]4[CH:25]=[C:26]([CH:34]=[CH:35][CH:36]=4)[O:27][CH2:28][C:29]([O-:31])=[O:30])[CH2:20][CH2:21][CH:22]=3)[O:10][C:11]=2[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1.[Na+:38]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 54507446Ethyl [3-[[2-(4,5-diphenyloxazol-2-yl)-2-cyclopenten-1-yl]methyl]phenoxy]acetate

생성물 1

HCID 75012223Sodium [3-[[2-(4,5-diphenyloxazol-2-yl)-2-cyclopenten-1-yl]methyl]phenoxy]acetate

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

To a solution of ethyl [3-[[2-(4,5-diphenyloxazol-2-yl)-2-cyclopenten-1-yl]methyl]phenoxy]acetate (400 mg) in ethanol (20 ml) was added 1N-sodium hydroxide solution (0.83 ml). After being stirred for 8 hours, the solvent was evaporated in vacuo. The residue was triturated in ether to give sodium [3-[[2-(4,5-diphenyloxazol-2-yl)-2-cyclopenten-1-yl]methyl]phenoxy]acetate (350 mg).

후처리

  1. customthe solvent was evaporated in vacuo
  2. customThe residue was triturated in ether

출처 및 근거

ORD 기록
ord-415b12324bcf45768929e9b6973a8d17
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06025375

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