Benzenesulfonyl chloride → HCID 15453203, 화합물

반응식

[C:1]1([S:7](Cl)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:11][C:12]1[O:16][N:15]=[C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:13]=1[Br:23]>>[Br:23][C:13]1[C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:15][O:16][C:12]=1[NH:11][S:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:9])=[O:8]

참가 물질

반응물 2

HCID 7369Benzenesulfonyl chloride

HCID 5829115-Amino-4-bromo-3-phenylisoxazole

생성물 1

HCID 15453203HCID 15453203, 화합물수율 36%

실험 절차

This compound was prepared from benzenesulfonyl chloride and 5-amino-4-bromo-3-phenylisoxazole according to the method in Example 25b in 36% yield. Recrystallization from methanol gave a yellow solid, m.p. 113-115° C.

후처리

customRecrystallization from methanol
customgave a yellow solid, m.p. 113-115° C.

출처 및 근거

ORD 기록: ord-4f468cfa6e8a4bd8bd3307bc674c7151
출처 데이터셋: uspto-grants-2000_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06030991

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